TIA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18296
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Cytotoxic granule associated RNA binding protein 1,Cytotoxic granule associated RNA binding protein,mTIA-1,Nucleolysin TIA 1 isoform p40 ,Nucleolysin TIA-1 isoform p40,Nucleolysin TIA1 isoform p40,p40 TIA 1,p40-TIA-1 (containing p15-TIA-1),p40-TIA-1,RNA binding protein TIA 1,RNA binding protein TIA1,RNA-binding protein TIA-1,T-cell-restricted intracellular antigen-1,TIA 1,TIA 1 cytotoxic granule associated RNA binding protein ,Tia,TIA-1,TIA1,TIA1 cytotoxic granule associated RNA binding protein,TIA1 cytotoxic granule associated RNA binding protein like 1,TIA1 protein,TIA1,TIAL1,TIAR,WDM,TIA1抗体 |
| Swissprot | P31483 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. |
Images
Western blot analysis of 293T Hela and HEPG2 cell lysates using TIA1 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TIA1 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TIA1 Polyclonal Antibody at dilution of 1:30(×200)
