TLR9 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70125
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | CD289,TLR 9,TLR9,Toll like receptor 9,Toll like receptor 9 isoform A precursor,Toll like receptor 9 isoform B,Toll-like receptor 9,TLR9抗体 |
| Swissprot | Q9EQU3,Q9NR96 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse TLR9 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:500 |
| Concentration | 1.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Lysosome, Membrane |
| Tissue specificity | Expressed in the basolateral region of gastric epithelial cells with high levels detected in antrum and body mucosa (at protein level). Detected in spleen and stomach at higher levels in C57BL/6 mice than BALB/C.Highest expression level in bone marrow macrophage. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. |
