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TNF alpha Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-33121

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC-p,IF

  • 详情
  • 文献(2)
  • Overview

    Synonyms APC1,APC1 protein,Cachectin,DIF,Differentiation inducing factor,Macrophage cytotoxic factor,Tnf,TNF superfamily,member 2,TNF,macrophage derived,TNF,monocyte derived,TNF-a,TNF-alpha,TNFA,TNFA,TNFSF2,Tumor necrosis factor alpha,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor Necrosis Factor,Membrane Form,Tumor necrosis factor,soluble form,TNF-α抗体
    Swissprot P01375
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthesized peptide derived from the Internal region of human TNF-α
    Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF
    Recommended dilution WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted and Cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
    Background Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
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