TNF beta Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14410
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | LTalpha,DIF,LT alpha,LT,LT-alpha,Lta,Lymphotoxin alpha (TNF superfamily,member 1),Lymphotoxin alpha,Lymphotoxin-alpha,TNF B,TNF superfamily member 1,TNF,lymphocyte-derived,TNF-beta,TNFB,TNFB,TNFbeta,TNFSF1,TNLG1E,Tumor necrosis factor beta,tumor necrosis factor ligand 1E,Tumor necrosis factor ligand superfamily member 1,LTA抗体 |
Swissprot | P01374 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human LTA |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. |