TNFRSF11B Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70067
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | MGC29565,OCIF,OPG,Osteoclastogenesis inhibitory factor,Osteoprotegerin,PDB5,TNF receptor superfamily member 11b,TNFRSF 11B,TNFRSF11B,TR 1,TR1,TR11B,Tumor necrosis factor receptor superfamily member 11B,TNFRSF11B抗体 |
| Swissprot | O08712,O08727 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200 |
| Concentration | 0.93 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Highly expressed in liver, lung, stomach, intestines and calvaria. Highly expressed in decidua and placenta, and in embryo.Highest expression level in decidua. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily.This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption.This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development.Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification.Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
