TNFRSF8 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16310
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | CD 30,CD30,CD30 antigen,CD30L receptor,Cytokine receptor CD30,D1S166E,KI 1,KI 1 antigen,Ki-1 antigen,KI1,Lymphocyte activation antigen CD30,TNFRSF 8,Tnfrsf8,TNR8,Tumor necrosis factor receptor superfamily member 8,TNFRSF8抗体 |
Swissprot | P28908 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human TNFRSF8 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.4mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm and Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |