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TNNT1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53126

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms ANM,MGC104241,NEM5,Skeletal,Slow ,slow skeletal muscle,Slow skeletal muscle troponin T,sTnT,Tnnt1,TNNT1,TNT,TnTs,Troponin T,Troponin T slow skeletal muscle,Troponin T type 1 (skeletal slow),troponin T1 skeletal slow,Troponin T1, slow skeletal type,TNNT1抗体
    Swissprot P13805
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human TNNT1
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:25-1:50;
    Concentration 0.66mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
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