TNNT2 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70232
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
Synonyms | Cardiac muscle troponin T,Cardiomyopathy dilated 1D (autosomal dominant),Cardiomyopathy hypertrophic 2,CMD1D,CMH2,CMPD2,cTnT,LVNC6,MGC3889,OTTHUMP00000033864,OTTHUMP00000033865,OTTHUMP00000033866,OTTHUMP00000033867,OTTHUMP00000033870,OTTHUMP00000218095,RCM3,TNNT 2,TNNT2,TNNT2,TnTc,Troponin T cardiac muscle,Troponin T type 2 (cardiac),Troponin T type 2 cardiac,Troponin T,cardiac muscle,Troponin T2 cardiac,TNNT2抗体 |
Swissprot | P50752,P50753 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin T |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:500 |
Concentration | 500 μg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoskeleton,cardiac Troponin complex,striated muscle thin filament,troponin complex,Cytosol,Other locations:cardiac myofibril,sarcomere |
Tissue specificity | Highest expression level in cardiac ventricle |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration.Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy.Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. |