TONSL Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10088
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | I kappa B related protein,I-kappa-B-related protein,IkappaBR,IKBR,Inhibitor of kappa B related protein,Inhibitor of kappa B-related protein,MMS22L-interacting protein,MMS22L-interacting protein,NFBIL2/TONSL,NF kappa B inhibitor like protein 2,NF-kappa-B inhibitor-like protein 2,NFBIL2,NFBIL2/TONSL,Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like protein 2,Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2,Protein IkappaBR,Tonsl,TONSL,Tonsoku-like protein,tonsoku-like,DNA repair protein,TONSL抗体 |
| Swissprot | Q96HA7 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human TONSL |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks. |
| Tissue specificity | Expressed in heart, skeletal muscle and tracheal epithelial cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription.The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA.Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. |
