UBB Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10015
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | UBB,UBB,Ubiquitin,UBB抗体 |
Swissprot | P0CG47 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human UBB |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. |
Images
Western Blot analysis of Mouse pancreas tissue, Hela cell and Mouse liver tissue, A549 and 293T cell using UBB Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer using UBB Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human colon cancer using UBB Polyclonal Antibody at dilution of 1:20