UBE2V1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52433
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | CIR1,CROC-1,CROC1,CROC1A,TRAF6-regulated IKK activator 1 beta Uev1A,UB2V1,UBE2V 1,UBE2V,UBE2V1,Ubiquitin conjugating enzyme E2 variant 1,Ubiquitin-conjugating enzyme E2 variant 1,UEV-1,UEV1,UBE2V1抗体 |
| Swissprot | Q13404 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Excluded from the nucleolus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family.They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s.The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene.It is thought to be involved in the control of differentiation by altering cell cycle behavior.Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified.Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
Images
Western blot analysis of 293T cell Mouse spleen tissue and Human spleen tissue lysates using UBE2V1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using UBE2V1 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using UBE2V1 Polyclonal Antibody at dilution of 1:40(×200)
