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VMA21 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53204

宿主: Rabbit

反应性: H,M

应用: IHC,IF

  • 详情
  • Overview

    Synonyms VMA21, Vacuolar ATPase Assembly Factor,Myopathy With Excessive Autophagy Protein,MEAX,XMEA,Vacuolar ATPase Assembly Integral Membrane Protein VMA21,VMA21 Vacuolar H+-ATPase Homolog (S. Cerevisiae),Myopathy With Excessive Autophagy,VMA21 Vacuolar H+-ATPase Homolo.,VMA21抗体
    Swissprot Q3ZAQ7
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human VMA21
    Application IHC(Detection kit: E-IR-R213),IF
    Recommended dilution IHC,,1:150-1:500;IF,,1:50-1:200
    Concentration 2.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,ER to Golgi transport vesicle membrane,Lysosome,Other locations:endoplasmic reticulum-Golgi intermediate compartment membrane,integral component of membrane
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.
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