ZFP36 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18447
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | G0/G1 switch regulatory protein 24,G0S24,GOS24,Growth factor-inducible nuclear protein NUP475,NUP475,Protein TIS11A,RNF162A,TIS 11,TIS11,TIS11A,Tristetraprolin,Tristetraproline,TTP,TTP,Zfp-36,ZFP36,Zinc finger protein 36,Zinc finger protein 36 homolog,Zinc finger protein 36, C3H type, homolog (mouse),Zinc finger protein, C3H type, 36 homolog,ZFP36抗体 |
Swissprot | P26651 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human ZFP36 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 0.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Cytoplasm. Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). |